A simple, specific, accurate and stability-indicating UV- Spectrophotometric method was developed for the estimation of ilaprazole, using a Shimadzu, model 1800 spectrophotometer and as a solvent methanol used at wave length (λmax) 306 nm. Linearity was established for ilaprazole in the range of 2-10 μg/ml. The percentage recovery of was found to be in the range of 99.22-100.21 %. The drug was subjected to acid, alkali and neutral hydrolysis, oxidation, dry heat, UV light and photolytic degradation. The proposed method for stability study shows that there was appreciable degradation found in stress condition of ilaprazole.
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